Molecular weight: 47 kD
Effectors: Hg2+, Ag+, Cr2+, Sn2+, Cu2+ and ionic detergents inhibit. Mg2+,
sodium cholate and BSA stabilize the enzyme. 4-Chloromercuribenzoate
(2 mmol/L), monoiodoacetate (2 mmol/L), NaF (20 mmol/L), NaN3 (20
mmol/L), EDTA (5 mmol/L) and 2-phenanthroline (2 mmol/L) do not
affect the enzyme activity while SDS (0.1% (w/v)) is inactivating.
pH optimum: 7.5
pH stability: 6.0-10.0
Thermal stability: Up to +50°C
Appearance: Brownish lyophilizate
Solubility: Clear, brown solution in water (c=50 mg/mL)
Activity (+25°C, cholesterol oleate): ≥10 U/mg lyophilizate
: ≤0.001
Uricase: ≤0.005
Stability: At +2 to +8°C within specification range for 12 months.
Store dry.