Immunogen: Human C-reactive protein
Related product: MAB<Digit>M-145A41 IgG
Properties
The polyclonal antibody IgG directed to c-reactive protein is produced
in sheep. It is prepared as solution containing protein (≥40 g/L); Tris
buffer with NaN3, 0.09% (w/v).
Recommended working concentration: 15 mg/mL
Remark: When stored over longer periods at +4°C, a slight turbidity
may occur which can easily be removed by centrifugation. No alteration
of antibody properties occurs thereby.
Specification
Appearance: Clear to slightly opalescent yellowish solution
pH value (+25°C): 7.8-8.2
Protein (Biuret): 50-60 mg/mL
Function: Calibration curve characterization defined by turbidimetric
measurement A340/A700
δA (Standard 1mg/dL): ≥0.038
δA (Standard 10mg/dL): ≥0.228
δA (Standard 25mg/dL): ≥0.370
pH 5.5 treatment (30 minutes): Corresponds to specification
Stability: At -15 to -25°C within specification range for 24 months.
Avoid repeated freezing and thawing.
Background information
C-reactive protein (CRP) is part of the β-globulin family found in human
plasma. Increased levels of CRP are involved in a variety of inflammatory
diseases. Furthermore elevated CRP serum levels indicate tissue injury,
transplant rejection, carcinogenesis and acute myocardial infarction.